Anti microbial effect of prebiotic containing tooth paste against streptococcus mutans and lactobacillus: An invitro evaluation

: To evaluate the antimicrobial efficacy of three commercially available toothpastes which are non-fluoridated, fluoridated and one containing prebiotic ingredient on s . Antimicrobial activities prebiotic, fluoridated, non-fluoridated were assessed at different concentrations (100ug, 200ug, 300ug 400ug). Since toothpaste had other proven agents, 100% inulin extract from chicory (prebiotic) was for its varying concentrations. property evaluated by determining zone inhibition using agar well diffusion method Luria Bertani (LB) broth media MRS forL.plantarum. 100ul inoculums S.mutans L.plantarum poured to plates respectively. Five wells measuring 0.5cm made, dentifrice concentration i.e; 100ug, 400ug loaded into respective wells. 50ul DMSO in centre as control incubated 37°C 24hrs. All tested significant activity against L.plantarum. The highest exhibited with mean (18.5+/-0.5) (20.0+/-1) There no difference (P=1), but there a (P<0.001). increased higher all Inulin extract. effective concentrations, most both micro-organisms.